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ProTrap Pro A Resin

ProTrap Pro A Resin

Affinity chromatography resin

ProTrap Pro A Resin is a next-generation affinity chromatography resin designed for efficient and high-purity purification of monoclonal and polyclonal antibodies, particularly IgG from various species. Incorporating a genetically engineered recombinant Protein A ligand, this resin offers enhanced alkaline stability and superior dynamic binding capacity compared to traditional Protein A resins. ProTrap Pro A is ideal for both research and bioprocessing applications, including antibody capture, polishing, and large-scale purification. It supports multiple regeneration cycles with minimal loss in performance and is fully compatible with standard chromatography systems, making it a robust and scalable solution for antibody-based workflows.

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ProTrap Pro A Resin 100 mL
ProTrap Pro A Resin, 100 mL
High-performance resin for efficient biomolecule separation.
PT-A-100ML
On Request
ProTrap Pro A Resin, 50 mL
High-performance resin for efficient biomolecule separation.
PT-A-50ML
On Request
Pack Size
100 mL
50 mL

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Properties
Matrix Crosslinked agarose beads
Ligand High molecular weight Dextran sulfate
Particle diameter (µm) 30–165 µm
Lysozyme binding capacity ≥20 mg/mL resin
Sulphur content 50 µM/mL
Recommended CIP solution 0.2(M) NaOH, 0.2(M) NaOH in 20% EtOH, 0.2(M) NaOH in 95% EtOH
pH stability range 1–13
Storage 2–8 °C in 20% ethanol
Characteristics of Protein Recovery Possible to enter the pore but low adsorption and high recovery under salt addition conditions

Applications

Protein A resin is a versatile tool used in various protein purification applications:

Advantages

High Affinity and Selectivity: Offers strong and specific binding for antibodies, minimizing non-specific interactions with other proteins.