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Recombinant Human IL-7 Protein

Recombinant Human IL-7 Protein

(Lyophilized, E.Coli coli-derived)

Catalog No: BTC-IL7-50 | Size: 50 µg

Overview

Our GMP grade Recombinant Human Interleukin-7 (IL-7) is a crucial cytokine involved in the development and survival of T cells, B cells, and NK cells. Produced in E.Coli

IL-7

Specifications

  • Expression System: Escherichia coli
  • Purity: ≥98% (SDS-PAGE and RP-HPLC)
  • Molecular Weight: ~17.5 kDa (153 amino acids)
  • Specific Activity: ≥2 × 10⁶ IU/mg (measured via 2E8 cell proliferation assay)
  • Endotoxin Level: <1 EU/µg (LAL assay)
  • Residual Host Cell DNA: <10 ng/mg (validated qPCR method)
  • Sterility: Free from mycoplasma, bacterial and viral contamination.
  • Formulation: Lyophilized powder, carrier-free
  • Reconstitution: Recommended in sterile water or 0.1% PBS
  • Storage: Store at 2-8°C (lyophilized) and –20°C after reconstitution.
  • Shelf Life: 24 months.

Use: Validated under GMP conditions for use in preclinical and clinical research.

Role:

IL-7 is a non-redundant cytokine essential for lymphoid lineage development and homeostasis. It plays a critical role in early B-cell development in the bone marrow and is a key survival factor for T cells in the thymus and periphery.

Applications

  • In vitro expansion of T cells and NK cells
  • Lymphoid lineage differentiation studies
  • Functional immunological assays and cytokine stimulation experiments
  • Supportive reagent in cell therapy, vaccine, and immunotherapy research
  • Standard for ELISA, flow cytometry, and blocking assays

Highlihgts

  • High biological activity and batch-to-batch consistency
  • Low endotoxin levels suitable for immune-sensitive cell models
  • Carrier-free formulation supports flexible use in cell culture
  • Produced in E.Coli coli, cost-effective and animal-origin free
  • Complies with USP (1043)
Available Sizes
Contact
10 µg | 50 µg | 100 µg | Bulk quantities
info@biotrum.co .com for quotes, COA, or custom orders

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